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What do we mean by nervous system regulation?

Daniel Holmqvist

A calm sea surface in soft light

You may have heard of the vagus nerve, the sympathetic and parasympathetic nervous systems, or body-based methods. But what does all of this actually mean?

Put simply, the body constantly shifts between activity and recovery. It is a natural system that helps us meet life’s challenges and then find our way back to rest.

With prolonged stress, pain or mental ill-health, it can become harder for the body to find its way back to recovery, even though you are in a safe place and no immediate danger exists. You may also have noticed that knowing you should relax does not always help. The body does not seem to listen anyway.

At Nūvai we therefore work with what we call nervous system regulation. Through breathing, movement and other body-based interventions, we want to create better conditions for the body’s natural ability to shift between activity and recovery.

The goal is not to remove difficult feelings but to create better conditions for safety, recovery and greater resilience to stress. When the body feels safe, it often becomes easier to handle stress, pain and life’s challenges.

How might it show up in everyday life?

For some, the body keeps running at full speed long after the workday has ended. For others, it can be hard to wind down after a conflict, to fall asleep despite being tired, or the body reacts strongly in situations you know are actually harmless.

It can also be the opposite. Instead of feeling wired, you may feel tired, shut down or find it hard to mobilise energy.

Imagine, for example, that you are about to give a presentation at work. Your heart beats faster, your breathing changes and your muscles tense. That is not a sign that something is wrong. The body is mobilising resources to meet a challenge. When the situation is over, we want the system to be able to shift back again.

It is precisely that flexibility we are interested in. The goal is not to be calm all the time. A well-functioning nervous system needs to be able both to activate when the situation demands it and to find its way back to recovery afterwards.

What does the research say?

Interest in nervous system regulation has grown rapidly in recent years. Research shows, among other things, that simple body-based methods, such as slow breathing, can affect the body’s physiology and strengthen the systems linked to rest and recovery.

At the same time, it is important not to oversimplify. The nervous system has no simple on/off switch, and there is no single exercise that ‘resets the vagus nerve’. Concepts like nervous system regulation describe a complex interplay between brain, body, environment and our experiences.

How do we work at Nūvai?

With us, body-based interventions can be part of a larger treatment. That may mean exploring breathing, movement, bodily sensations and different ways of influencing the level of activation in the body. They can also be used as part of augmented therapy—for example in preparation for a dosing session, as support close to the treatment itself, and in the integration that follows.

We are not trying to teach the body to always be calm. Instead, we want to increase the ability to move between different states and find the way back to recovery once the load has passed.

Going forward, we believe that understanding the interplay between body and mind will take an ever larger place in the treatment of stress and mental ill-health. Rather than seeing thoughts, feelings and bodily reactions as separate parts, we need to understand the human being as one coherent system.

For us at Nūvai, the body is therefore not just something that reacts to how we feel. It can also be a way into change.

Answers to our most common questions.

Is esketamine treatment legal in Sweden?

Yes, esketamine treatment is legal in Sweden when prescribed by a licensed physician. Esketamine has been used medically for over 50 years and is an approved medicine. At Nūvai the treatment is administered under controlled conditions by qualified medical staff, in accordance with current regional guidelines.

What does the treatment cost?

Nūvai's goal is that precision therapy, with or without treatment additions, should be accessible to everyone who needs it. Today the treatment is paid for privately, but we are working towards being able to cover all or part of it through private insurers or health insurance (within the high-cost protection scheme) in the future. The cost varies depending on the treatment plan and individual needs. A digital screening call costs SEK 2,500. Ketamine-assisted therapy starts from 33,000 kr. We also offer the option to pay in instalments via Klarna. You are welcome to contact us for a personal and free cost estimate.

How many sessions are needed?

The number of sessions depends on the type of treatment, your needs and how you respond to it. The plan is followed up and adjusted continuously together with your therapist. For ketamine-assisted precision psychotherapy the model is inspired by international protocols where ketamine is usually given as a series of six infusions over about four weeks. Psilocybin-assisted therapy takes place abroad and usually involves 1–2 dosing sessions over a week, with time for local preparation and integration. Breathwork as a treatment addition is usually provided twice a week for four weeks, either at the clinic or online. The exact scope is always tailored to your situation, your goals and your response to treatment.

Can I continue with my current medication?

In most cases you can continue with your existing medication, but this is assessed individually by our physicians who are specialists in psychiatry and anaesthesia. Some medicines may need to be adjusted ahead of treatment, and sometimes it is desirable to taper off or change them afterwards. We help you with this if you wish. At the initial consultation our physicians review your full medication list and give concrete recommendations. Never make changes to your medication without consulting your care provider.

Can I be referred by my doctor or psychologist?

Absolutely. We accept referrals from other care providers and they can contact us directly by email at info@nuvai.se. You are also welcome to apply for an assessment yourself — a referral is not a requirement to begin treatment with us. Please be careful not to write personal data in emails to us.